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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Alex Guerrero# | 35 | 2045 | |
| 2 | Frank Bourne# | 32 | 2045 | |
| 3 | Mark Henderson# | 25 | 2045 | |
| 4 | Casey Hoover# | 22 | 2045 | |
| 5 | Bobby Ojeda# | 19 | 2045 | |
| 6 | Edwin Macias# | 18 | 2045 | |
| 7 | Ronny Vallesteros# | 15 | 2045 | |
| 7 | Rich Espinoza# | 15 | 2045 | |
| 9 | Chad Perez# | 14 | 2045 | |
| 10 | Carlos Garcia# | 12 | 2045 | |
| 10 | Erik Wilson# | 12 | 2045 | |
| 10 | Chris Pinsent# | 12 | 2045 | |
| 13 | Charlie Frey# | 11 | 2045 | |
| 13 | Gustavo Monreal# | 11 | 2045 | |
| 15 | Branden Williams# | 10 | 2045 | |
| 16 | Mike Guzman# | 9 | 2045 | |
| 16 | Jose Valdes# | 9 | 2045 | |
| 18 | Carlos Martinez# | 8 | 2045 | |
| 19 | David Zamarripa# | 7 | 2045 | |
| 20 | Kevin Hubert# | 6 | 2045 | |
| 21 | Jean Mary# | 5 | 2045 | |
| 22 | Lucas Buchan# | 4 | 2045 |
